************************** Quick Links ************************** The table below describes the types of functions that can be performed in ISB-CGC and provides links to documentation on how to do those functions. +---------------------------------------+---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------+-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------+ |Function |In GUI |With Command Line | +=======================================+=============================================================================================================================================================================================================================================================================================+=================================================================================================================================================================================================================================================================================================+ |**Work on the Google Cloud Platform** |- `Link to the Google Cloud Platform Console `_ |- `Google Cloud SDK `_ | | |- Getting a trial account on the Google Cloud Platform `sponsored by Google `_ |- `Google Cloud Shell `_ | | |- Getting a trial account on the Google Cloud Platform `sponsored by ISB-CGC `_ |- `Authenticating with Google `_ (two approaches: `gcloud init `_ and/or `gcloud auth login `_) | | |- General information on how to use the `Google Cloud Platform Console `_ | | | |- `Specific information `_ on how to set up your GCP project for use with ISB-CGC | | | |- How to `manage project members and change member permissions `_ | | +---------------------------------------+---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------+-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------+ |**Explore what data are available** |- `Documentation `_ |- BigQuery `R and Python Tutorials `_ | | |- `GUI `_ |- `ISB-CGC Endpoints `_ | | | |- `Google Genomics APIs `__ | +---------------------------------------+---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------+-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------+ |**Understand details of the data** |- `Access controlled data `_ |- For data in BigQuery | | |- `View File List `_ in GUI | - BigQuery `Command Line Tool `_ | | |- `View Sequences with IGV `_ | - BigQuery `REST API `_ | | |- `Google BigQuery Web UI `_ |- For data in Google Cloud Storage | | |- `Google API Explorer `_ | - Google `Cloud Storage JSON API `_ | | | | - Google Cloud Storage `gsutil `_ | | | |- For data in Google Genomics | | | | - `Google Genomics REST API `_ | +---------------------------------------+---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------+-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------+ |**Analyze ISB-CGC data** |- `Analyses `_ with Bar Charts, Histograms, Scatter Plots, Violin Plots, Cubby Hole Plots and SeqPeek |- BigQuery `R and Python Tutorials `_ | | |- `Google BigQuery Web UI `_ and `BigQuery UI Walkthrough `__ |- ISB-CGC `Endpoints `_ | | | |- `Google Genomics APIs `__ | +---------------------------------------+---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------+-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------+ |**Create cohorts of patients** |- `Create cohorts `_ |- Use GUI saved cohorts in ISB-CGC `Endpoints `_ | | |- Cohorts `set operations `_ |- de novo using ISB-CGC `Endpoints `_, BigQuery `Command Line Tool `_, and/or BigQuery `REST API `_ | | |- Create a cohort from visualization (`background `_ and `tool image `_) | | | |- Develop queries with `Google BigQuery Web UI `_ and/or `Google API Explorer `_ before creating cohorts with command line tools | | +---------------------------------------+---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------+-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------+ |**Add your data to the cloud** |- Uploading your low level data (e.g. Bam and VCF files) to `Google Cloud Storage `_ |- Uploading your data to Google `Cloud Storage `_ | | |- `Upload high level summary data `_ (such as Methylation, Gene Expression, microRNA, Protein Expression & Customized data) for plotting in the UI. |- Uploading your data to Google `BigQuery `_ | | | | | +---------------------------------------+---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------+-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------+ |**Analyze your data with ISB-CGC data**|- `Plot your high level experimental data `_ (such as Methylation, Gene Expression, microRNA, Protein Expression and Customized data) with other ISB-CGC data (e.g. TCGA). |- BigQuery `R and Python Tutorials `_ | | | |- ISB-CGC `Endpoints `_ | | | |- `Google Genomics APIs `__ | +---------------------------------------+---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------+-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------+ |**Run bioinformatics pipelines/tools** | |- Google Compute Engine `getting started guide `_ | | | |- `Compute examples in Github `_ (with Common Workflow Language (CWL) and grid examples) | | | |- `Useful recipes `_ in the `Google Genomics Cookbook `_ | +---------------------------------------+---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------+-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------+ |**Import Genomic Data Commons lists** | |- `Introduction `_ | | | |- `Importing GDC File Manifests `_ | | | |- `Importing GDC Case lists `_ | 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